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. Author manuscript; available in PMC: 2024 Mar 11.
Published in final edited form as: Mol Psychiatry. 2023 Jul 14;28(10):4463–4473. doi: 10.1038/s41380-023-02172-2

Fig. 1. Cognitive impairment evaluated by novel object recognition (NOR) task in APP/PS1 mice challenged with CLP.

Fig. 1

A Schematic representation of the NOR task. B, D Exploration time at 30 and 120 after CLP and non-CLP surgery. No difference between the control and sepsis groups was observed in the locomotor activity. C, E Recognition index, as explained in Materials and Methods. The results are expressed as the mean ± SEM for n = 7–10. Unpaired Student’s t-tests analyzed the differences between control and sepsis at each time point. *p < 0.05 compared to controls.