Table 2.
Cancer incidence among veterans with sleep disorders (1999-2010, N=663,869, VISN-7).
| Cancer Site | Crude | Adjusted2 | ||
|---|---|---|---|---|
| Hazard Ratio | 95% CI | Hazard Ratio | 95% CI | |
| All Cancer | Any Sleep Disorder | |||
| 1.75 | (1.66, 1.86) | 1.45 | (1.37, 1.54) | |
| Prostate | 1.73 | (1.58, 1.90) | 1.50 | (1.37, 1.64) |
| Colorectal | 1.52 | (1.32, 1.75) | 1.34 | (1.16, 1.54) |
| Female Breast | 2.87 | (1.50, 5.49) | 1.69 | (0.88, 3.24) |
| Other1 | 1.75 | (1.60, 1.91) | 1.45 | (1.33, 1.59) |
| All Cancer | Insomnia | |||
| 1.73 | (1.58, 1.89) | 1.39 | (1.27, 1.52) | |
| Prostate | 1.64 | (1.43, 1.90) | 1.39 | (1.20, 1.60) |
| Colorectal | 1.46 | (1.17, 1.82) | 1.22 | (0.98, 1.51) |
| Female Breast | 2.98 | (1.21, 7.30) | 1.78 | (0.73, 4.38) |
| Other1 | 1.84 | (1.61, 2.10) | 1.46 | (1.28, 1.67) |
| All Cancer | Sleep Apnea | |||
| 1.70 | (1.55, 1.84) | 1.44 | (1.32, 1.57) | |
| Prostate | 1.72 | (1.51, 1.96) | 1.52 | (1.38, 1.73) |
| Colorectal | 1.48 | (1.21, 1.81) | 1.38 | (1.12, 1.69) |
| Female Breast | 3.31 | (1.22, 8.99) | 1.90 | (0.69, 5.17) |
| Other1 | 1.59 | (1.39, 1.82) | 1.37 | (1.20, 1.57) |
| All Cancer | Other Sleep Disorders 3 | |||
| 1.68 | (1.46, 1.94) | 1.47 | (1.28, 1.70) | |
| Prostate | 1.69 | (1.35, 2.11) | 1.54 | (1.23, 1.92) |
| Colorectal | 1.53 | (1.08, 2.16) | 1.41 | (0.99, 1.99) |
| Female Breast4 | – | – | – | – |
| Other1 | 1.68 | (1.35, 2.09) | 1.47 | (1.18, 1.83) |
1 Includes: lung, pancreas, kidney, brain, bladder, liver, ovary, esophagus, stomach, skin (melanoma). 2 Adjusted for: age, sex (except for gender specific cancers), marital status, state or residence. CI: confidence interval. 3 Includes: hypersomnias, parasomnias, circadian rhythm sleep disorders, movement disorders, arousal disorders. VISN-7, Veterans Integrated Service Network 7 (AL, GA, SC). 4 Data too sparse for evaluation.