Table 3:
Associations between arsenic exposurea and performance on three tasks of the CANTAB, stratified by urinary %MMA and intake of B-vitamins
| CANTAB test | Outcome | %MMA (n=228) | B-vitamin index (n=249) | Folate intakeb (n=249) | |||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Efficient methylators (n=115) | Inefficient methylators (n=113) | Low (n=124) | High (n=125) | Low (n=125) | High (n=124) | ||
| Stockings of Cambridge | # Problems solved in minimum moves | −0.03 (−0.07, 0.01) |
0.01 (−0.01, 0.04) |
−0.03 (−0.08, 0.02) |
0.02 (−0.01, 0.04) |
−0.01 (−0.05, 0.03) |
0.004 (−0.02, 0.03) |
| Intra – Extra Dimensional Set Shift | # Stages completed | −0.02 (−0.03, 0.0001) |
−0.002 (−0.02, 0.02) |
−0.02 (−0.04, 0.01) |
−0.01 (−0.02, 0.003) |
−0.01 (−0.03, 0.01) |
−0.02 (−0.04, −0.01) |
| Total # errors | 0.30 (−0.08, 0.69) |
−0.13 (−0.53, 0.28) |
0.26 (−0.29, 0.81) |
0.03 (−0.18, 0.25) |
0.05 (−0.42, 0.52) |
0.46 (0.08, 0.84) |
|
| # Pre- Executive Shift Error | −0.05 (−0.11, 0.02) |
−0.12 (−0.24, 0.0001) |
−0.07 (−0.12, −0.02) |
−0.09 (−0.17, −0.01) |
−0.15
(−0.26, −0.05) |
0.004
(−0.04, 0.05) |
|
| # Post-Executive Shift Error | 0.18 (0.002, 0.26) |
0.01 (−0.31, 0.33) |
0.17 (−0.05, 0.40) |
0.07 (−0.11, 0.25) |
0.08 (−0.21, 0.37) |
0.23 (0.04, 0.43) |
|
| Spatial Span | Span length | −0.02 (−0.03, −0.005) |
0.002 (−0.01, 0.01) |
−0.02 (−0.04, 0.002) |
−0.004 (−0.01, 0.004) |
−0.01 (−0.02, −0.01) |
−0.01 (−0.03, 0.004) |
| Spatial Span Total errors | −0.03 (−0.09, 0.02) |
0.02 (−0.06, 0.11) |
−0.04 (−0.13, 0.04) |
0.02 (−0.02, 0.05) |
0.02 (−0.04, 0.07) |
−0.08 (−0.13, −0.02) |
|
a
Modeled as specific gravity-adjusted sum of urinary inorganic arsenic, monomethylarsonous acid, and dimethylarsinic acid,
b
adjusted for total energy intake and expressed as grams/1000 kcal; Models adjusted for age, sex, maternal education, possessions score, Home Observation for Measurement of the Environment Inventory score, season, school clusters