Table 3. Inpatients characteristics and penalized maximum likelihood logistic regression of typed RSV-cases without co-infection*.
| n RSV-A/B (%B) | OR (95% Ci) | p | Adjusted OR (95% Ci) † | Adjusted p-value† | |
|---|---|---|---|---|---|
| Age group | |||||
| 0-3m | 53/79 (59.9) | Ref. | Ref. | ||
| 3-6m | 23/41 (64.1) | 1.19 (0.64–2.19) | 0.581 | 1.31 (0.70–2.46) | 0.397 |
| 6-12m | 24/18 (42.9) | 0.51 (0.25–1.02) | 0.057 | 0.55 (0.27–1.11) | 0.096 |
| 1-2y | 36/45 (55.6) | 0.84 (0.48–1.46) | 0.536 | 1.00 (0.56–1.78) | 0.993 |
| 2-5y | 24/22 (47.8) | 0.62 (0.32–1.21) | 0.159 | 0.73 (0.37–1.45) | 0.373 |
| Sex | |||||
| Male | 84/118 (58.4) | Ref. | Ref. | ||
| female | 76/87 (53.4) | 0.82 (0.54–1.23) | 0.335 | 0.78 (0.51–1.20) | 0.264 |
| Hospital | |||||
| Ullevål | 85/98 (53.5) | Ref. | Ref. | ||
| AHUS | 35/47 (57.3) | 1.16 (0.69–1.96) | 0.575 | 1.20 (0.70–2.04) | 0.510 |
| Østfold | 40/60 (60.0) | 1.30 (0.79–2.12) | 0.301 | 1.28 (0.77–2.13) | 0.337 |
| Study season | |||||
| 2015/2016 | 44/77 (63.6) | Ref. | Ref. | ||
| 2016/2017 | 93/91 (49.5) | 0.56 (0.35–0.90) | 0.016 | 0.55 (0.32–0.95) | 0.032 |
| 2018/2019 | 23/37 (61.7) | 0.92 (0.49–1.73) | 0.787 | 0.95 (0.49–1.83) | 0.873 |
| Length of stay | |||||
| <24 hours | 35/40 (53.3) | Ref. | Ref. | ||
| > = 24 hours | 125/165 (56.9) | 1.16 (0.70–1.92) | 0.575 | 1.17 (0.70–1.96) | 0.543 |
| Respiratory support ‡ | |||||
| No | 121/152 (55.7) | Ref. | Ref. | ||
| Yes | 36/50 (58.1) | 1.10 (0.68–1.80) | 0.696 | 1.11 (0.66–1.86) | 0.700 |
| Acute upper respiratory tract infection (URTI) | |||||
| No | 146/189 (56.4) | Ref. | Ref. | ||
| Yes | 14/16 (53.3) | 0.88 (0.42–1.84) | 0.734 | 0.83 (0.39–1.76) | 0.629 |
| Lower respiratory tract infection (LRTI) | |||||
| No | 15/16 (51.6) | Ref. | Ref. | ||
| Yes | 145/189 (56.6) | 1.22 (0.59–2.53) | 0.586 | 1.20 (0.56–2.56) | 0.633 |
| Congenital heart disease or pulmonary disease (including BPD) | |||||
| No | 145/193 (57.1) | Ref. | Ref. | ||
| Yes | 15/12 (44.4) | 0.61 (0.28–1.32) | 0.206 | 0.62 (0.28–1.38) | 0.244 |
| Comorbidity § | |||||
| No | 136/190 (58.3) | Ref. | Ref. | ||
| Yes | 24/15 (38.5) | 0.45 (0.23–0.89) | 0.021 | 0.49 (0.25–0.99) | 0.046 |
| Gestational age <37 weeks | |||||
| No | 140/180 (56.3) | Ref. | Ref. | ||
| Yes | 20/25 (55.6) | 0.97 (0.52–1.80) | 0.919 | 1.04 (0.54–1.98) | 0.917 |
* Patients co-infected with one or more of Influenza, Metapneumovirus, Parainfluenza 1, 2, 3, 4 and Adenovirus, or cases with missing information about coinfections are excluded from this table.
†Age groups, month of hospital contact, and the treating hospital were included as independent variables
‡ Invasive ventilation, Continuous Positive Airway Pressure (CPAP), or Bi-level Positive Airway Pressure (BiPAP)
§ Including trisomy 21, neuromuscular, impairment, congenital heart disease, pulmonary disease, BPD, immunodeficiency, and cancer.