TABLE 4.
Correlations Between Entorhinal and Perirhinal Vacuolization Scores and Neuropathologic Features in Dementia With Lewy Bodies (DLB) and Alzheimer Disease (AD) Cases
| AD (N = 40) |
DLB (N = 40) |
|||
|---|---|---|---|---|
| EC | PC | EC | PC | |
|
| ||||
| GLB | 0.347 | 0.000 | 0.193 | −0.012 |
| MF plaques | 0.047 | 0.295 | 0.191 | 0.056 |
| IP plaques | 0.035 | 0.316 | 0.069 | 0.083 |
| ST plaques | 0.121 | 0.518** | 0.097 | 0.396 |
| HP plaques | 0.039 | 0.099 | 0.150 | 0.303 |
| MF NP | 0.206 | 0.420 | − 0.082 | − 0.004 |
| IP NP | 0.283 | 0.530** | 0.141 | 0.146 |
| ST NP | 0.244 | 0.570** | − 0.05 | 0.072 |
| HP NP | 0.021 | 0.217 | 0.036 | 0.251 |
| MF tangles | 0.127 | 0.573** | 0.147 | 0.12 |
| IP tangles | 0.174 | 0.437 | 0.11 | 0.172 |
| ST tangles | 0.072 | 0.574** | 0.028 | 0.275 |
| HP tangles | 0.015 | 0.36 | − 0.205 | 0.247 |
| MF amyloid | − 0.196 | − 0.144 | 0.127 | 0.345 |
| IP amyloid | − 0.155 | − 0.232 | 0.051 | 0.125 |
| ST amyloid | −0.037 | 0.244 | −0.047 | 0.175 |
| HP amyloid | − 0.126 | − 0.117 | − 0.097 | 0.268 |
| Braak stage | 0.395 | 0.436 | 0.127 | 0.315 |
**
P < 0.01.
AD indicates Alzheimer disease; DLB, dementia with Lewy body; EC, entorhinal cortex; GLB, global Lewy body score; HP, hippocampal; IP, inferior parietal; MF, mid-frontal; NP, neuritic plaque; PC, perirhinal cortex; ST, superior temporal.