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. 2024 Mar 5;44(2):289–302. doi: 10.19852/j.cnki.jtcm.20240203.007

Figure 3. Effect of the method of replenishing Qi and activating blood on the ultrastructure of hippocampus and cortical blood vessels in APP/PS1 double transgenic ischemic mice.

Figure 3

A: ultrastructure of brain tissue hippocampus; B: ultrastructure of cortical blood vessels. Scale bars = 500 nm. A1/B1: C57 sham-operated group; A2/B2: C57 ischemia group; A3/B3: APP/PS1 model group; A4/B4: APP/PS1 ischemia group; A5/B5: C57BL ischaemic + aspirin group at dose of 20 mg·kg-1·d-1 A6/B6: C57BL ischaemic + SLT group at dose of 32 mg·kg-1·d-1; A7/B7: APP/PS1 + SLT group at dose of 32 mg·kg-1·d-1; A8/B8: APP/PS1 ischaemic + donepezil hydrochloride group at dose of 32 mg·kg-1·d-1; A9/B9: APP/PS1 ischaemic + SLT group at dose of 32 mg·kg-1·d-1. Ischaemic treatment: both right and left common carotid arteries were separated, and the arterial blood vessel was stimulated with a temperature-controlled current of 80 mu A using an in vivo thrombometer to cause thrombosis. Duration: two months. SLT: Sailuotong; APP: amyloid precursor protein; PS1: presenilin-1.