Table 1.

Effect of the method of replenishing Qi and activating blood on the spatial learning and memory ability of APP/PS1 double transgenic ischemic mice ($\bar{x}±s$)

Group	Dose (mg·kg-1·d-1)	n	Number of crossings	Swimming time (s)	Swimming distance (cm)
C57 sham-operated	-	16	7.1±1.3	46.9±12.2	318.3±89.2
C57 ischemia	-	16	5.2±1.3a	39.1±10.4a	252.1±101.4a
APP/PS1 model	-	16	4.2±2.1a	37.2± 9.9a	275.2±97.3e
APP/PS1 ischemia	-	16	3.4±1.7a	33.0±11.2a	237.2±98.3e
C57BL ischaemic + aspirin	32	16	6.1±1.7b	45.4±12.4b	198.3±124.8b
C57BL ischaemic + SLT	32	16	6.4±1.7b	43.3±13.4b	298.2±69.9f
APP/PS1 + SLT	32	16	5.7±2.1c	46.3±9.3d	305.3±89.5d
APP/PS1 ischaemic + donepezil hydrochloride	20	16	5.3±2.2c	45.5±11.3c	333.6±76.7c
APP/PS1 ischaemic + SLT	32	16	6.8±2.2f	44.2±8.0f	341.3±81.1f

Notes: ischaemic treatment: both right and left common carotid arteries were separated, and the arterial blood vessel was stimulated with a temperature-controlled current of 80 mu A using an in vivo thrombometer to cause thrombosis. The APP/PS1 ischaemic + donepezil hydrochloride group were administered intragastrically with 20 mg·kg^-1·d^-1 of donepezil hydrochloride. The C57BL ischaemic + aspirin group were administered intragastrically with 32 mg·kg^-1·d^-1 of aspirin, the SLT group were administered intragastrically with 32 mg·kg^-1·d^-1 of SLT and the control group were given 32 mg·kg^-1·d^-1 of solvent. Duration: two months. SLT: Sailuotong; APP: amyloid precursor protein; PS1: presenilin-1presenilin-1. One-way analysis of variance was employed to make comparisons among groups, and in the case of the normal distribution, Tukey’s post hoc test was conducted; otherwise, the Kruskal-Wallis test was adopted. Compared with C57 sham-operated group, ^aP < 0.01, ^eP < 0.05; compared with C57 ischemia group, ^bP < 0.05; ^fP < 0.01; compared with APP/PS1 ischemia group, ^dP < 0.05; ^c P < 0.01.