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. 2023 Dec 19;8(2):100237. doi: 10.1016/j.shj.2023.100237

Table 2.

The published relative risk reduction from registration trial, observed event rate in this observational study, and the hypothetical number needed to treat to prevent or postpone individual adverse outcomes

Outcome Published relative risk reduction Observed event rate NNT
All-cause hospitalization 0.24 94.3 per 100 person-years 4.4
HF hospitalization 0.47 24.3 per 100 person-years 8.8
All-cause death 0.38 49.5% 5.3

Abbreviations: HF, heart failure; NNT, number needed to treat.