Table 2.
The association between sTfR index and all-cause, CVD, and cancer mortality.
| All-cause mortality | CVD-related mortality | Cancer-related mortality | |||||||
|---|---|---|---|---|---|---|---|---|---|
| No. event | HR (95% CI) | p-value | No. event | sHR (95% CI)a | p-value | No. event | sHR (95% CI)a | p-value | |
| Model 1 | |||||||||
| Per SD increment | 231 | 1.19 (1.07–1.32) | 0.001 | 53 | 1.17 (0.92–1.49) | 0.21 | 60 | 1.22 (1.01–1.48) | 0.043 |
| Tertile 1 | 70 | 1.00 (Ref.) | — | 15 | 1.00 (Ref.) | — | 17 | 1.00 (Ref.) | — |
| Tertile 2 | 65 | 0.97 (0.69–1.37) | 0.870 | 14 | 1.10 (0.53–2.30) | 0.800 | 17 | 0.96 (0.49–1.89) | 0.906 |
| Tertile 3 | 96 | 1.62 (1.17–2.25) | 0.004 | 24 | 2.46 (1.25–4.83) | 0.012 | 26 | 1.60 (0.84–3.03) | 0.157 |
| Model 2 | |||||||||
| Per SD increment | 231 | 1.20 (1.07–1.34) | 0.002 | 53 | 1.06 (0.79–1.41) | 0.721 | 60 | 1.25 (1.03–1.51) | 0.032 |
| Tertile 1 | 70 | 1.00 (Ref.) | — | 15 | 1.00 (Ref.) | — | 17 | 1.00 (Ref.) | — |
| Tertile 2 | 65 | 0.96 (0.68–1.36) | 0.816 | 14 | 1.02 (0.48–2.16) | 0.966 | 17 | 1.00 (0.50–2.02) | 0.992 |
| Tertile 3 | 96 | 1.55 (1.11–2.16) | 0.010 | 24 | 1.73 (0.86–3.51) | 0.139 | 26 | 1.80 (0.93–3.48) | 0.090 |
| Model 3 | |||||||||
| Per SD increment | 231 | 1.25 (1.08–1.45) | 0.003 | 53 | 1.18 (0.83–1.68) | 0.375 | 60 | 1.38 (1.07–1.77) | 0.018 |
| Tertile 1 | 70 | 1.00 (Ref.) | — | 15 | 1.00 (Ref.) | — | 17 | 1.00 (Ref.) | — |
| Tertile 2 | 65 | 1.08 (0.74–1.57) | 0.689 | 14 | 1.19 (0.54–2.64) | 0.674 | 17 | 1.19 (0.56–2.53) | 0.654 |
| Tertile 3 | 96 | 1.71 (1.14–2.57) | 0.011 | 24 | 2.48 (1.05–5.87) | 0.053 | 26 | 2.29 (1.02–5.14) | 0.053 |
Model 1: unadjusted; model 2: adjusted for age, sex, ethnicity, smoking status, drinking status, and education; and model 3: further adjusted for BMI, SBP, DBP, albumin, total cholesterol, serum creatinine, serum potassium, hemoglobin, MCV, diabetes, hypertension, CVD, cancer, and ferritin.
Sub-distribution hazard ratio accounting for the competing event.