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. 2023 Nov 22;241(4):701–715. doi: 10.1007/s00213-023-06497-2

Table 2.

Comparison of ERT accuracy and overall latency and hormones among On AAS, Off AAS, and WLC groups. CANTAB ERT tests statistics and significance values are based on Tukey’s HSD test, hormone comparisons are based on Kruskal-Wallis

Measure WLC, N = 771 Off, N = 341 On, N = 451 F/H2 d WLC vs. Off d WLC vs. On d Off vs. On F3
Overall RT 1592.19 (628.31) 1653.90 (628.63) 1560.73 (511.24) 0.24 0.10 −0.06 −0.16 0.12
Overall 0.65 (0.08) 0.63 (0.07) 0.59 (0.09) 7.48** −0.29 −0.68** −0.47 6.87*
Happiness 0.80 (0.15) 0.82 (0.13) 0.78 (0.15) 0.99 0.20 −0.12 −0.33 0.76
Sadness 0.71 (0.18) 0.71 (0.16) 0.66 (0.19) 1.34 −0.03 −0.28 −0.27 1.17
Anger 0.53 (0.13) 0.53 (0.13) 0.45 (0.15) 5.31* −0.05 −0.57* −0.57 4.93*
Disgust 0.68 (0.20) 0.67 (0.16) 0.57 (0.22) 4.76* 0.01 −0.51* −0.55 4.53*
Surprise 0.71 (0.14) 0.68 (0.18) 0.71 (0.17) 0.50 −0.2 −0.02 0.16 0.64
Fear 0.47 (0.23) 0.36 (0.24) 0.38 (0.23) 3.80* −0.48 −0.41 0.07 3.21
Testosterone 19.74 (7.13) 13.49 (7.58) 44.06 (41.79) 20.22*** −0.85** 0.81* 1.02***
  Missing 31 6 15
TE 1.19 (1.02) 1.83 (1.78) 54.97 (49.24) 75.16*** 0.44 1.54*** 1.53***
  Missing 6 2 5
SHBG 42.91 (19.89) 32.57 (16.26) 19.61 (15.77) 30.26*** −0.57* −1.30*** −0.81**
  Missing 30 4 14
FSH 5.25 (3.02) 3.78 (2.38) 0.67 (2.01) 55.17*** −0.54* −1.79*** −1.41***
  Missing 30 4 13
LH 4.76 (1.81) 3.50 (1.66) 0.25 (0.71) 67.26*** −0.73* −3.27*** −2.54***
  Missing 30 4 13
Estradiol 82.00 (31.17) 78.41 (28.05) 204.60 (184.05) 15.15*** −0.12 0.93** 0.96**
  Missing 29 5 15
FTI 4.87 (1.30) 4.24 (2.41) 65.73 (121.72) 23.94*** −0.32* 0.71*** 0.71***
  Missing 31 5 15

RT reaction time, TE testosterone/epitestosterone ratio, SHBG sex hormone-binding globulin, FSH follicle-stimulating hormone, LH luteinizing hormone, FTI free testosterone index, d Cohen’s d

***p < 0.001, **p < 0.01, *p < 0.05 (false discovery rate adjusted)

1Mean (SD)

2F statistic for ERT measures, H statistic for hormones

3F statistic adjusted for age, IQ, and education

pFDR < 0.05 WLC vs On based on post-hoc Tukey HSD