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. 2024 Feb 27;12:1291230. doi: 10.3389/fchem.2024.1291230

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Copyright © 2024 Rehman, Saleem, Raza, Bashir, Muhammad, Asghar, Qamar, Shah, Bin Jardan, Mekonnen and Bourhia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of C. haematocephala extracts (CHnHE and CHME) on histopathological scale in acetic acid induced ulcerative colitis. Histopathological scale was quantified by inflammatory changes using histopathological slide examination given in Figure 9. This figure shows dose dependent decrease in histopathological scale after treatment with CHnHE and CHME (250, 500, and 750 mg/kg doses) standardized with prednisone (2 mg/kg) in comparison (p < 0.001) to CCG. One-way ANOVA followed by post hoc Tukey’s test was appliedto analyze the significance of differences among groups. Here, “a”, “b”, and “c” indicate significant differences from CCG, NCG and SCG respectively.