FIGURE 7.

Effect of C. haematocephala extracts (CHnHE and CHME) on macroscopic ulcer score (A) and ulcer index (B) in acetic acid induced ulcerative colitis. Figure shows significant dose dependent decline in macroscopic ulcer score and ulcer index after treatment for consective 11 days with CHnHE and CHME (250, 500, and 750 mg/kg doses) standardized with prednisone (2 mg/kg) in comparison (p < 0.001) to CCG. One-way ANOVA followed by post hoc Tukey’s test was applied to analyze the significance of differences among all treatment and control groups. Here, “a,” “b,” and “c” indicate significant differences from CCG, NCG, and SCG respectively.