Table 3.
Comparisons of histopathological results among four groups
| Parameters (mean ± SD) | BS group (n = 5) | B group (n = 6) | S group (n = 5) | C group (n = 6) | χ2 | p |
|---|---|---|---|---|---|---|
| Volume (cm3) | 0.928 ± 0.186 | 1.072 ± 0.153 | 1.034 ± 0.125 | 1.208 ± 0.449 | 1.263 | 0.738 |
| Necrotic fraction | 0.330 ± 0.098 | 0.230 ± 0.093 | 0.226 ± 0.063 | 0.165 ± 0.068 | 7.965 | 0.047 |
| Microvessel density | 23.533 ± 2.036 | 26.333 ± 2.936 | 29.600 ± 4.991 | 30.167 ± 3.811 | 9.545 | 0.023 |
| Histopathological SD | 9.958 ± 0.945 | 10.719 ± 1.195 | 12.701 ± 0.866 | 13.901 ± 2.212 | 13.972 | 0.003 |
Significant results reported in bold characters. Data are expressed as mean ± SD. B Bufalin treatment, BS Bufalin plus sorafenib treatment, C control, S Sorafenib treatment, SD Standard deviation