Table 4.
Quantitative comparison of the proposed workflows in terms of the requirements for pathologist review as fraction of the current reviewed cases, TFF3 staining as fraction of the current cases, observed prevalence of BE, sensitivity and specificity (with 95% CIs in parentheses)
Proposed ML-assisted workflow | Pathologist review | TFF3 staining | Observed prevalence | Sensitivity | Specificity |
---|---|---|---|---|---|
Pathologist reviews any positives | 48% (41–55%) | 100% | 17% (14–20%) | 1.00 (1.00–1.00) | 1.00 (1.00–1.00) |
Pathologist reviews H&E model positives | 37% (31-45%) | 37% (31–45%) | 19% (16–24%) | 0.91 (0.84–0.96) | 1.00 (1.00–1.00) |