Table 1.
EEG power bands
| State | Power band | WT prodromal (6–8 weeks) | WT Parkinsonian (14–18 weeks) | MCI prodromal (6–8 weeks) | MCI Parkinsonian (14–18 weeks) | Genotype | Age | Interaction |
|---|---|---|---|---|---|---|---|---|
| Wake | Alpha (8–11 Hz) | 15.6 ± 0.8% | 15.4 ± 0.4% | 14.0 ± 0.6% | 12.2 ± 1.3% | p < 0.01**, F = 8.0 | p = 0.21, F = 1.6 | p = 0.30, F = 1.1 |
| NREM | Delta (0.5–4 Hz) | 39.3 ± 1.5% | 42.5 ± 2.1% | 46.8 ± 1.5% | 49.1 ± 2.0% | p < 0.05*, F = 4.9 | ***, p < 0.001, F = 12.5 | p = 0.24, F = 1.6 |
| NREM | Alpha (8–11 Hz) | 10.3 ± 0.5% | 12.1 ± 0.5% | 9.6 ± 0.4% | 9.9 ± 0.4% | p < 0.01**, F = 7.3 | p = 0.09, F = 3.0 | p = 0.23, F = 1.5 |
| REM | Alpha (8–11 Hz) | 16.7 ± 0.7% | 19.9 ± 0.8% | 15.0 ± 0.6% | 14.4 ± 1.5% | p < 0.001***, F = 14.2 | p = 0.24, F = 1.4 | p = 0.49, F = 3.9 |
Relative EEG spectral power in the alpha (8–11 Hz) and delta (0.5–4 Hz) bands during wake, NREM sleep, and REM sleep in wildtype and MCI-Park mice. Relative power is calculated as the power of the frequency band (i.e., alpha or delta) divided by the overall power of the signal. It is expressed as a percentage ± standard error of measurement. Data analyzed by generalized linear models (GLM) two-way analysis of variance (ANOVA). N = 10–23 mice per genotype per age. All data presented in this table were collected at Northwestern University.
*p < 0.05; **p < 0.01; ***p < 0.001. Statistically significant results (p < 0.05) are shown in bold text.