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. 2024 Mar 11;14:5919. doi: 10.1038/s41598-024-54603-x

Table 1.

Maternal and perinatal characteristics of the study population.

Controls FGR p-value
N 111 97
Maternal characteristics
 Age (years) 33.8 ± 4.5 34.1 ± 5.7 0.668
 Nulliparous (%) 40 (36.0) 34 (35.0) 0.944
 Body mass index (kg/m2) 23.0 ± 4.8 23.2 ± 4.6 0.736
 Use of assisted reproductive technologies (%) 14 (12.6) 14 (14.4) 0.747
 Smokers (%) 15 (13.5) 9 (9.3) 0.404
Feto-placental ultrasound
 Gestational age at ultrasound (weeks) 33.1 ± 3.5 33.2 ± 3.5 0.886
 Estimated fetal weight (g) 2173 ± 734 1640 ± 667  <0.001
 Umbilical artery PI 0.95 ± 0.19 1.18 ± 0.47  <0.001
 Middle cerebral artery PI 1.95 ± 0.39 1.79 ± 0.40 0.013
 Cerebroplacental ratio 2.07 ± 0.52 1.67 ± 0.54  <0.001
 Uterine arteries mean PI 0.72 ± 0.19 1.07 ± 0.54  <0.001
 Ductus venosus PI 0.45 ± 0.17 0.52 ± 0.27 0.168
Perinatal data
 Gestational age at delivery (weeks) 39.9 ± 1.1 37.3 ± 3.4  <0.001
 Prematurity (%) 3 (2.7) 22 (22.7)  <0.001
 Birthweight (g) 3338 ± 383 2191 ± 627  <0.001
 Birthweight percentile 49 ± 29 4 ± 4  <0.001
 Female sex (%) 48 (43.2) 46 (47.4) 0.546
 Preeclampsia (%) 2 (1.8) 18 (18.6)  <0.001
 Need for neonatal reanimation (%) 4 (3.6) 19 (19.6)  <0.001
 Admission to Neonatal Intensive Care Unit (%) 2 (1.8) 7 (7.2) 0.035
 Neonatal morbidity (%) 11 (9.9) 39 (40.2)  <0.001

Data shown as mean ± SD or n (percentage).

Statistically significant different variables (< 0.05) variables are highlighted using bold text.