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. 2023 Oct 26;21(5):1066–1079. doi: 10.1016/j.gpb.2023.10.004

Figure 4.

Figure 4

Monitoring of SARS-CoV-2 lineage evolution globally and regionally

A. Number of released genome sequences and the median mutation frequency along sequence sampling date. The mutation frequency is calculated by dividing the total mutation of each sequence by the genome length. B. Stacking diagram showing the proportion of top 3 prevalent Pango lineages or WHO-defined variants per week. VUMs are currently circulating variants under monitoring that include BA.2.75, CH.1.1, XBB*, XBB.1.9.1, XBB.1.9.2, and XBB.2.3 Pango lineages as of 19 June 2023. Meanwhile, VOIs are currently circulating variants of interest that include XBB.1.5 and XBB.1.16 Pango lineages as of 27 June 2023. C. Heatmap showing the frequency of the cumulative sequences for randomly selected lineages in China. D. Distribution of the number of genome sequences released in China along sequence sampling date. The blue vertical line represents the number of genome sequences released daily in China, and the green line represents the dynamic accumulation of SARS-CoV-2 genome sequences released in China. E. Pie chart showing the lineage proportions in Hubei Province in China from July 1 to October 24 in 2023. VUM, variant under monitoring; VOI, variant of interest.