TABLE 2.
Tumor formation in chickensa
| Expt no. | CEF expressing: | No. of animals injected | No. of animals with tumors after wk:
|
|||||
|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | |||
| I | - | 4 | 0 | 0 | 0 | |||
| v-Jun | 6 | 0 | 0 | 0 | ||||
| v-Jun-m1 | 7 | 4 | 5 | 6 | ||||
| II | - | 5 | 0 | 0 | ||||
| v-Jun | 6 | 0 | 1 | |||||
| v-Jun-m1 | 6 | 6 | 6 | |||||
| III | ATF2 | 4 | 0 | 0 | 0 | 0 | ||
| v-Jun | 5 | 0 | 0 | 2 | 4 | |||
| v-Jun + ATF2 | 6 | 0 | 0 | 2 | 5 | |||
| v-Jun-m1 | 5 | 3 | 5 | 5 | ||||
| v-Jun-m1 + ATF2 | 6 | 6 | 6 | 6 | ||||
| IV | ATF2 | 4 | 0 | 0 | 0 | 0 | ||
| v-Jun | 7 | 0 | 0 | 0 | 1 | |||
| v-Jun + ATF2 | 7 | 0 | 0 | 0 | 1 | |||
| v-Jun-m1 | 7 | 1 | 1 | 4 | ||||
| v-Jun-m1 + ATF2 | 7 | 5 | 5 | 5 | ||||
a
Infected CEFs (2 × 106 in 0.1 ml of medium) were injected subcutaneously in the wing web of 1-day-old SPAFAS chickens. Tumor formation was scrutinized every week after injection. All of the animals were dissected; no obvious internal tumors were detected.