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. Author manuscript; available in PMC: 2024 Mar 12.
Published in final edited form as: Nat Med. 2023 Feb 23;29(3):700–709. doi: 10.1038/s41591-023-02217-7

Extended Figure 1. Fecal 5-ASA levels according to self-reported 5-ASA use in the IBDMDB.

Extended Figure 1.

We determined 5-ASA use according to detection of drug levels in stool using LC-MS, defined as detection of fecal 5-ASA levels > 10e7. Concordance, determined according to statistical accuracy (Methods), between self-reported use of 5-ASA and detection of fecal 5-ASA was 80.3%. Users (light blue) had 5-ASA levels which were ~10,000x greater than non-users (navy blue). Each individual is represented by multiple points on this graph given that participants provided multiple samples across the year-long cohort. Boxplots show median and lower/upper quartiles; whiskers show inner fences.