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. Author manuscript; available in PMC: 2024 Mar 12.
Published in final edited form as: Nat Med. 2023 Feb 23;29(3):700–709. doi: 10.1038/s41591-023-02217-7

Extended Table 10. Presence of 5-ASA inactivating acetyltransferases.

Gene prevalence (%) varies across participants with IBD, but does not vary significantly by 5-ASA status (GLMM p≥0.07), arguing for effect modification of the effects of 5-ASA on prevention of disease relapse. Among participants without IBD prevalence rates of these enzymes also appear similar.

5-ASA users 5-ASA nonusers Non-IBD
UniRef90 ID
C7H1G6 47.8 52.3 67.0
R5CY66 17.4 20.3 43.7
R6CZ24 20.7 14.3 28.5
T5S060 14.1 9.2 12.3