Extended Table 8. Presence of 5-ASA metabolizing acetyltransferases are associated with steroid use in the HMP2.
Odds ratios with 95% CI are presented. Analyses were adjusted for age, sex, disease type (CD vs. UC), host acetylation phenotype, and smoking status.
| Feature | ||
|---|---|---|
| Genes | Absent | Present |
| C7H1G6 | 1 (referent) | 2.81 (1.68-4.68) |
| R5CY66 | 1 (referent) | 2.88 (1.66-5.00) |
| R6CZ24 | 1 (referent) | 2.58 (1.40-4.77) |
| T5S060 | 1 (referent) | 3.24 (1.63-6.42) |
| Host factors | ||
| Disease type | UC | CD |
| 1 (referent) | 3.11 (1.85-5.21) | |
| Age, y | 0.92 (0.89-0.94) |