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. Author manuscript; available in PMC: 2024 Mar 12.
Published in final edited form as: J Diabetes Complications. 2023 Jun 8;37(8):108527. doi: 10.1016/j.jdiacomp.2023.108527

Table 2.

1- and 2-year changes in risk factors overall and for NDPP enrollees and non-enrollees, and adjusted change in risk factors among NDPP enrollees and non-enrollees.a

Overall Enrollees Non-enrollees p-Value N used in model Adjusted mean change in risk factor among enrolleesa (95 % CI) Adjusted mean change in risk factor among non-enrolleesa (95 % CI) p-Value
Number (N) 8131 776 7355
One-year changes
BMI (kg/m2) −0.2 ± 2.5 −1.2 ± 2.4 −0.1 ± 2.4 <0.001 5145 −1.1 (−1.3 to −0.8) −0.1 (−0.3 to 0.1) <0.001
Blood pressure (mmHg)
 Systolic 0 ± 16 −2 ± 15 0 ± 16 0.002 4910 −2 (−3 to 0) 0 (−1 to 1) 0.003
 Diastolic 0 ± 11 −1 ± 11 0 ± 11 0.0325 4910 −1 (−2 to 0) 0 (−1 to 1) 0.002
Lipids (mg/dl)
 Total cholesterol −2 ± 30 −6 ± 32 −1 ± 30 0.032 1952 −8 (−12 to −3) −3 (−6 to 0) 0.022
 HDL-c 0 ± 8 1 ± 8 0 ± 8 0.561 1947 1 (−1 to 2) 0 (0 to 1) 0.881
 Triglycerides −8 ± 89 −27 ± 103 −6 ± 87 0.004 1936 −30 (−42 to −18) −10 (−18 to −2) <0.001
 LDL-c −2 ± 26 −4 ± 25 −2 ± 26 0.091 2537 −5 (−9 to −2) −3 (−5 to −1) 0.100
HbA1c (%) 0.0 ± 0.6 −0.1 ± 0.4 0.0 ± 0.6 <0.001 2382 −0.1 (−0.2 to 0.0) 0.0 (0.0 to 0.1) <0.001
Two-year changes
BMI (kg/m2) −0.1 ± 2.9 −0.6 ± 2.7 −0.1 ± 2.9 <0.001 4760 −0.5 (−0.8 to −0.2) −0.2 (−0.4 to 0.0) 0.009
Blood pressure (mmHg)
 Systolic 1 ± 16 0 ± 16 1 ± 16 0.151 4556 −1 (−2 to 1) 0 (−1 to 1) 0.084
 Diastolic −1 ± 11 −1 ± 11 0± 11 0.129 4556 −1 (−2 to 0) 0 (−1 to 0) 0.010
Lipids (mg/dl)
 Total cholesterol −1 ± 33 −2 ± 31 −1 ± 33 0.718 1536 −4 (−10 to 2) −2 (−6 to 1) 0.586
 HDL-c 1 ± 8 1 ± 7 0 ± 8 0.155 1553 1 (−1 to 3) 1 (0 to 1) 0.534
 Triglycerides −8 ± 89 −27 ± 103 −6 ± 87 0.004 1936 −30 (−42 to −18) −10 (−17 to −2) <0.001
 LDL-c −3 ± 28 −4 ± 28 −3 ± 29 0.302 2461 −6 (−10 to −2) −4 (−6 to −1) 0.169
HbA1c (%) 0.1 ± 0.6 0.0 ± 0.5 0.1 ± 0.6 0.039 2293 0.0 (−0.1 to 0.1) 0.1 (0.0 to 0.1) 0.219
a

Adjusted for baseline age group, sex, race, and value of the risk factor.