Table 2.
Methodological papers
| Focus of paper | Numbers (n/34) | First author and reference | |
| N | % | ||
| Cohort designs for clinical areas | 6 | 18 | Ahmed,63 Couwenberg,18 Gal,62 Heaven,74 Young-Afat,65 Zakrzewska75 |
| CmRCT/TwiCs design | 17 | 50 | Bibby,76 Candlish,77 Clegg,78 Flory,79 Kim,80 Lambin,81 Pate,82 Relton,2 11 Reeves54 Richards,83 Van der Velden,59 Verkooijen,84 Verweij,66 Vickers,85 Viksveen,16 Young-Afat17 |
| Learning Health Systems (using TwiCs) | 1 | 3 | Wouters73 |
| Studies within a Trial (SWATs) using cohorts | 10 | 30 | Arundel,86 Cockayne,60 Cotterill,87 Boyd,88 Goodwin,89 Knapp,90 Ni,91 Loban,92 Maruani,93 Wakabayashi94 |
CmRCT, cohort multiple RCT; TwiCs, Trials within Cohorts.