Table 2.
Cox regression analysis for prediction of OS in 149 patients with low tumor burden
| Variables | Univariable analysis |
Multivariable analysis |
||
|---|---|---|---|---|
| HR (95% Cl) | p value | HR (95% Cl) | p value | |
| Age, 1 year increase | 1.00 (0.98–1.03) | 0.818 | 1.00 (0.97–1.02) | 0.839 |
| Male (vs. female) | 0.77 (0.43–1.39) | 0.392 | 0.81 (0.43–1.51) | 0.503 |
| FIB-4 index, 1 point increase | 1.07 (1.02–1.13) | 0.006 | 1.01 (0.94–1.09) | 0.779 |
| ALBI score, 1 point increase | 2.41 (1.50–2.44) | <0.001 | 2.13 (1.13–4.00) | 0.019 |
| AFP, 1 ng/mL increase | 1.00 (1.00–1.00) | 0.660 | ||
| HBV positive (vs. negative) | 1.02 (0.59–1.75) | 0.943 | ||
| HCV positive (vs. negative) | 1.37 (0.79–2.38) | 0.261 | ||
| Cirrhosis (vs. no) | 1.79 (0.97–3.22) | 0.063 | ||
| SR versus TACE | 0.54 (0.31–0.94) | 0.029 | 0.82 (0.43–1.55) | 0.532 |
OS, overall survival; HR, hazard ratio; Cl, confidence interval; FIB-4 index, fibrosis-4 index; ALBI score, albumin-bilirubin score; AFP, a-fetoprotein; HBV, hepatitis B virus; HCV, hepatitis C virus; SR, surgical resection; TACE, transarterial chemoembolization.