Pharmacokinetic prediction properties of the two pyrazolo[1,5-a]pyrimidines 12a and 12b.
| Parameter | 12a | 12b |
|---|---|---|
| CYP1A2 inhibitor | Yes | Yes |
| CYP2C19 inhibitor | Yes | Yes |
| CYP2C9 inhibitor | Yes | Yes |
| CYP2D6 inhibitor | No | No |
| CYP3A4 inhibitior | Yes | Yes |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.