Figure 5.

ABX administration significantly decreases gut microbiota diversity in the asthma mouse model. (A) Shannon index of mouse gut microbiota. (B) Chao index of mouse gut microbiota. Alpha diversity refers to the diversity within a specific region or ecosystem. Typical measurements include Shannon and Chao indices. The Shannon index primarily reflects the species diversity in a sample. The Shannon index value is directly proportional to the diversity of species. (C) Principal coordinate analysis. The X-axis and Y-axis represent the two selected principal axes, while the percentage indicates the degree of difference in sample composition between the principal axes. The scales of the X-axis and Y-axis are relative distances with no practical significance. The different colors or shapes represent samples of different groupings. The closeness of the two sample points indicates that the species composition is similar). ^**P<0.01. OVA, ovalbumin; ABX, antibiotics; OTU, operational taxomic unit.