Table 2.
Outcomes and complications in kidney transplant recipients who had conventional dressing or ciNPWT with unmatched, obese, and propensity score matching analyses.
| Variable | Unmatched | BMI ≥30 kg/m2 | PSM | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Conventional dressing (n = 97) | ciNPWT/Prevena™ (n = 30) | Total (n = 127) | p-value | Conventional dressing (n = 19) | ciNPWT/Prevena™ (n = 16) | Total (n = 35) | p-value | Conventional dressing (n = 26) | ciNPWT/Prevena™ (n = 26) | Total (n = 52) | p-value | |||
| Primary outcome | ||||||||||||||
| Wound complication, n (%) | 20 (20.6) | 7 (23.3) | 27 (21.3) | 0.75 | 7 (36.8) | 5 (31.3) | 12 (34.3) | 0.73 | 6 (23.1) | 6 (23.1) | 12 (23.1) | 1.00 | ||
| Secondary outcomes | ||||||||||||||
| Surgical site infection, n (%) | 5 (5.2) | 4 (13.3) | 9 (7.1) | 0.21 | 3 (15.8) | 3 (18.8) | 6 (17.1) | 1.00 | 2 (7.7) | 3 (11.5) | 5 (9.6) | 1.00 | ||
| Wound dehiscence, n (%) | 12 (12.4) | 6 (20) | 18 (14.2) | 0.29 | 6 (31.6) | 4 (25) | 10 (28.6) | 0.72 | 5 (19.2) | 5 (19.2) | 10 (19.2) | |||
| Superficial dehisc., n (%) | 9 (9.3) | 6 (20) | 15 (11.8) | 0.19 | 3 (15.8) | 4 (25) | 7 (20) | 0.23 | 3 (11.5) | 5 (19.2) | 8 (15.4) | 0.28 | ||
| Deep fascial dehisc., n (%) | 3 (3.1) | 0 (0) | 3 (2.4) | 3 (15.8) | 0 (0) | 3 (8.6) | 2 (7.7) | 0 (0) | 2 (3.8) | |||||
| Return to OT (wound), n (%) | 5 (5.2) | 3 (10) | 8 (6.3) | 0.39 | 3 (15.8) | 2 (12.5) | 5 (14.3) | 1.00 | 2 (7.7) | 2 (7.7) | 4 (7.7) | 1.00 | ||
| PFC treatment, n (%) | 7 (7.2) | 0 (0) | 7 (5.5) | 0.20 | 1 (5.3) | 0 (0) | 1 (2.9) | 1.00 | 1 (3.8) | 0 (0) | 1 (1.9) | 1.00 | ||
| Hematoma, n (%) | 4 (4.1) | 3 (10) | 7 (5.5) | 0.35 | 1 (5.3) | 1 (6.3) | 2 (5.7) | 1.00 | 1 (3.8) | 2 (7.7) | 3 (5.8) | 1.00 | ||
| Use of NPWT, n (%) | 8 (8.2) | 3 (10) | 11 (8.7) | 0.72 | 4 (21.1) | 1 (6.3) | 5 (14.3) | 0.35 | 4 (15.4) | 3 (11.5) | 7 (13.5) | 1.00 | ||
| Time to wound healing (days), median (IQR) | 89 (28–126) | 53 (30–72) | 0.28 | 129 (115–164) | 54 (41–64) | 0.03* | 101 (76–150) | 53 (30–72) | 0.20 | |||||
| Length of stay, median (IQR) | 7 (6–12) | 7 (6–14) | 0.78 | 7 (7–12) | 6.5 (6–14.7) | 0.78 | 9 (7–13) | 7 (6–12) | 0.20 | |||||
| ASEPSIS score, median (IQR) | 0 (0–5.5) | 15.5 (4.2–30) | 0.02* | 16 (1.0–52.5) | 20.5 (5.7–42) | 0.99 | 4 (0–33) | 14 (3.5–36) | 0.55 | |||||
| Graft loss, n (%) | 2 (2.1) | 1 (3.4) | 3 (2.4) | 0.56 | 0 (0) | 1 (6.3) | 1 (2.9) | 0.46 | 0 (0) | 0 (0) | 0 (0) | |||
| DGF, n (%) | 31 (32) | 11 (36.7) | 42 (33.1) | 0.63 | 8 (42.1) | 7 (43.8) | 15 (42.9) | 0.92 | 10 (38.5) | 10 (38.5) | 20 (38.5) | 1.00 | ||
| Extra immunosuppress., n (%) | 24 (24.7) | 11 (36.7) | 35 (27.6) | 0.20 | 3 (15.8) | 6 (37.5) | 9 (25.7) | 0.14 | 8 (30.8) | 8 (30.8) | 16 (30.8) | 1.00 | ||
| Drain days, median (IQR) | 5 (3–16) | 4 (3–12) | 0.95 | 8 (5–10) | 4 (4–12) | 0.99 | 4 (2–10) | 7 (3–13) | 0.81 | |||||
| Follow-up days, median (IQR) | 78 (58–140) | 85 (70–129) | 0.82 | 103 (55–187) | 90 (55–156) | 0.75 | 63 (48–192) | 85 (71–115) | 0.47 | |||||
For categorical variables where the cell count was <5, p-values were obtained with Fisher’s Exact test.
BMI, body mass index; ciNPWT, closed-incision negative pressure wound therapy; Dehisc., dehiscence; DGF, delayed graft function; immunosuppress., immunosuppression; NPWT, negative pressure wound therapy; OT, operating theater; PFC, perigraft fluid collection; PSM, propensity score matching.
*p < 0.05.