Table 2.

Results of subgroup analysis of the association between B7-H3 expression and clinicopathological parameters

Outcome of interest	Studies(n)	Patients	OR (95%CI)	P value	Model	Heterogeneity
						I2(%)	P value
Age (≥ 65 vs. <65 years)	3	325	2.09(1.29,3.39)	0.003	Fixed	0	0.99
Gender (Male vs. Female)	6	753	0.78(0.52,1.19)	0.25	Fixed	0	0.56
Tumor grade (low vs. high)	4	370	1.50(0.90,2.52)	0.12	Fixed	0	0.7
LN metastasis (Positive vs. negative)	5	708	1.20(0.85,1.68)	0.3	Fixed	26	0.25
Depth of infiltration
Ta-2 vs. T3-4	5	708	0.63(0.45,0.88)	0.007	Fixed	10	0.35
NMIBC vs. MIBC	5	869	1.03(0.57,1.83)	0.93	Random	51	0.09
NMIBC (Ta/Tis vs. T1)	2	590	1.83(0.27,12.33)	0.54	Random	69	0.07
MIBC (T2 vs. T3-4)	4	555	0.62(0.42,0.92)	0.02	Fixed	0	0.57
Recurrence vs. No recurrence	4	880	2.21(1.67,2.92)	< 0.00001	Fixed	11	0.34

LN: Lymph node