Table 2.
The minimum PLT value during follow-up and the treatment response of 350 SLE-TP patients with different aPLs
| aPLs+(n = 194) | aPLs- (n = 156) |
P | ||||
|---|---|---|---|---|---|---|
| 1 aPL+ (n = 75, 38.7%) |
2 aPLs+ (n = 51, 26.2%) |
3 aPLs+ (n = 68, 35.1%) |
aPLs + total | |||
| Minimum platelet count (×109/L) | 45(21,73) | 32(11,71) | 31.5(12.5,50) | 37(15,64) | 51(27,76) | 0.002 |
| Severe(<20 × 109/L), n(%) | 16(21.3) | 19(37.3) | 22(32.4) | 57(29.4) | 28(17.9) | 0.010 |
| Moderate(20–50 × 109/L), n(%) | 27(36.0) | 13(25.5) | 26(38.2) | 66(34.0) | 48(30.8) | |
| Mild(50–100 × 109/L), n(%) | 32(42.7) | 19(37.3) | 20(29.4) | 71(36.6) | 80(51.3) | |
| Latest platelet count (×109/L) | 125(85,211) | 147(90,222) | 100.5(64,172) | 123(79,209) | 141(82,212) | 0.361 |
| CR, n(%) | 69(92.0) | 42(82.4) | 55(80.9) | 166(85.6) | 135(86.5) | |
| R, n(%) | 1(1.3) | 2(3.9) | 7(10.3) | 10(5.2) | 1(0.6) | 0.021 |
| NR, n(%) | 5(6.7) | 7(13.7) | 6(8.8) | 18(9.3) | 20(12.8) | |
| Loss of CR or R, n(%) | 41(54.7) | 28(54.9) | 44(64.7) | 113(58.2) | 69(44.2) | 0.009 |
Note:CR, complete response,is defined as platelet count recovered to at least 100 × 109/L. R, response, is defined as the restoration of the platelet count to a range 30 and 100 × 109/L and along with at least a twofold increase from the baseline count. NR, nonresponse,is recorded when the platelet count remained below 30 × 109/L or did not double from the baseline count. Loss of CR or R, is denoted by a platelet count falling below 100 × 109/L (for those in CR), or dropping below 30 × 109/L or failing to achieve at least a twofold increase from the baseline count (for those in R)