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. 2024 Mar 11;24:758. doi: 10.1186/s12889-024-18272-9

Table 2.

Association between TyG and OA

OR (95% CI), p value
Model 1 Model 2 Model 3
Osteoarthritis
TyG index 9.52 (4.13, 21.92) < 0.0001 8.54 (3.41, 21.37) < 0.0001 7.34 (2.25, 23.93) 0.0010
Categories
Quartile 1 Reference Reference Reference
Quartile 2 1.26 (0.94, 1.68) 0.1217 1.15 (0.85, 1.56) 0.3523 1.12 (0.82, 1.54) 0.4760
Quartile 3 1.76 (1.34, 2.32) < 0.0001 1.60 (1.20, 2.14) 0.0015 1.62 (1.17, 2.25) 0.0036
Quartile 4 1.93 (1.47, 2.54) < 0.0001 1.76 (1.31, 2.35) 0.0002 1.69 (1.18, 2.42) 0.0039
P for trend 9.52 (4.13, 21.92) < 0.0001 1.49 (1.24, 1.79) < 0.0001 1.45 (1.16, 1.83) 0.0014

Data are presented as ORs, 95% CIs, and P-value

Model 1: adjusted for nothing

Model 2: adjusted for age, gender, and race

Model 3: adjusted for age, gender, race, education level, PIR, smoke status, alcohol consumption, hypertension, diabetes, moderate physical activity, BMI, HDL cholesterol, LDL cholesterol, insulin, HOMA-IR, ALT, AST, CRP, BUN, and UA

ALT: alanine transaminase; AST: aspartate aminotransferase; BMI: body mass index; BUN: blood urea nitrogen; CI: confidence interval; CRP: C-Reactive Protein; HDL cholesterol: high-Density Lipoprotein Cholesterol; HOMA-IR, homeostatic model assessment of insulin resistance; LDL cholesterol: low-Density Lipoprotein Cholesterol; OR: odds ratio; PIR:Poverty-to-income ratio; TyG: Triglyceride–Glucose; UA; uric acid