Table 2.
The embryo quality of different total Gn dosage groups with AMH stratification
| AMH levels | Total Gn dosage (IU) | P value | ||||
|---|---|---|---|---|---|---|
| < 1875 (A) | 1875–3750 (B) | ≥ 3750 (C) | PAB | PAC | PBC | |
| The top-day3 embryo rate (%) | ||||||
| Age < 35 Y | ||||||
| AMH ≤ 1 ng/ml | 0 | 64.54 (1307/2025) | 62.51 (1154/1846) | – | – | 0.192 |
| 1 < AMH ≤ 3 ng/ml | 69.16 (5449/7879) | 65.16(12,975/19913) | 63.07 (1433/2272) | < 0.001 | < 0.001 | 0.049 |
| 3 < AMH ≤ 5 ng/ml | 69.82 (12,360/17702) | 67.01 (8224/12272) | 69.61 (268/385) | < 0.001 | 0.955 | 0.296 |
| AMH > 5 ng/ml | 69.61 (10,935/15710) | 68.20 (4383/6427) | 0 | 0.040 | – | – |
| Age 35–42 Y | ||||||
| AMH ≤ 1 ng/ml | 0 | 62.43 (525/841) | 62.77 (1182/1883) | – | – | 0.864 |
| 1 < AMH ≤ 3 ng/ml | 68.09 (638/937) | 64.37 (4029/6259) | 63.76 (1443/2263) | 0.028 | 0.020 | 0.609 |
| 3 < AMH ≤ 5 ng/ml | 70.56 (1299/1841) | 66.60 (1892/2841) | 62.99 (97/154) | 0.005 | 0.055 | 0.381 |
| AMH > 5 ng/ml | 69.82 (835/1196) | 70.89 (699/986) | 0 | 0.605 | – | – |
| The blastocyst formation rate (%) | ||||||
| Age < 35 Y | ||||||
| AMH ≤ 1 ng/ml | 0 | 44.10 (340/771) | 40.73 (255/626) | – | – | 0.211 |
| 1 < AMH ≤ 3 ng/ml | 57.32 (2423/4227) | 52.65 (5023/9540) | 46.73 (472/1010) | < 0.001 | < 0.001 | < 0.001 |
| 3 < AMH ≤ 5 ng/ml | 60.40 (6091/10084) | 56.27 (3806/6764) | 50.96 (106/208) | < 0.001 | 0.006 | 0.136 |
| AMH > 5 ng/ml | 61.29 (5841/9530) | 60.07 (2278/3792) | 0 | 0.194 | – | – |
| Age 35–42 Y | ||||||
| AMH ≤ 1 ng/ml | 0 | 38.38 (104/271) | 36.14 (219/606) | – | – | 0.545 |
| 1 < AMH ≤ 3 ng/ml | 48.21 (243/504) | 44.62 (1285/2880) | 36.81 (325/883) | 0.146 | < 0.001 | < 0.001 |
| 3 < AMH ≤ 5 ng/ml | 54.68 (532/973) | 49.09 (704/1434) | 48.39 (30/62) | 0.008 | 0.359 | 1.000 |
| AMH > 5 ng/ml | 57.72 (430/745) | 54.95 (333/606) | 0 | 0.321 | – | – |
| The high-quality blastulation rate (%) | ||||||
| Age < 35 Y | ||||||
| AMH ≤ 1 ng/ml | 0 | 11.41 (88/771) | 9.90 (62/626) | – | – | 0.386 |
| 1 < AMH ≤ 3 ng/ml | 20.44 (864/4227) | 17.40 (1660/9540) | 13.96 (141/1010) | < 0.001 | < 0.001 | 0.006 |
| 3 < AMH ≤ 5 ng/ml | 22.58 (2277/10084) | 19.90 (1346/6764) | 20.19 (42/208) | < 0.001 | 0.451 | 0.930 |
| AMH > 5 ng/ml | 23.05 (2197/9530) | 23.97 (909/3792) | 0 | 0.266 | – | – |
| Age 35–42 Y | ||||||
| AMH ≤ 1 ng/ml | 0 | 7.38 (20/271) | 6.77 (41/606) | – | – | 0.774 |
| 1 < AMH ≤ 3 ng/ml | 15.87 (80/504) | 13.58 (391/2880) | 10.76 (95/883) | 0.185 | 0.007 | 0.029 |
| 3 < AMH ≤ 5 ng/ml | 21.07 (205/973) | 17.02 (244/1434) | 17.74 (11/62) | 0.014 | 0.630 | 1.000 |
| AMH > 5 ng/ml | 21.61 (161/745) | 16.17 (98/606) | 0 | 0.012 | – | – |
PAB: < 1875 IU group vs. 1875–3750 IU group. PAC: < 1875 IU group vs. ≥ 3750 IU group. PBC: 1875–3750 IU group vs. ≥ 3750 IU group. AMH anti-Müllerian hormone, Gn gonadotropin. P < 0.05 was considered statistically significant. -, not applicable