Table 2. Functional outcomes after DAIR.
| Report details | Study type | Study time period | PJI type | Study groups | Follow-up period | Outcomes |
|---|---|---|---|---|---|---|
| Iza et al., 2019, Spain | Retrospective cohort | 2004–2016 | Included acute post-operative and acute haematogenous (symptoms <3 weeks) | 26 patients | Mean 3.4 (range, 1–12) years | KSS of 75 in DAIR failure group vs. 65 in treatment success group (non-significant difference) |
| Barros et al., 2019, Portugal | Retrospective case-control | 2010–2016 | Acute post-operative infection | (I) DAIR (26 patients); (II) Matched controls (52 patients) | Mean 42.1 (range, 24–66) months | No significant difference in all KOOS domains (pain, activities, sports, quality of life and other symptoms) after successful DAIR and primary TKA |
| Son et al., 2017, Korea | Retrospective cohort | 2010–2014 | PJI within 4 weeks of primary TKA, or acute haematogenous with ≤5 days symptoms | 25 patients | Mean 29.4 (range, 24–35) months | In treatment success cohort, mean Lysholm score of 81.4, mean KKS 79.4, ROM 115.4±12.9° |
| Dzaja et al., 2015, Canada | Retrospective cohort | 1991 - 2011 | Included acute post-operative and acute haematogenous (symptoms ≤4 weeks) | (I) DAIR (54 patients); (II) 2SR (91 patients); (III) matched primary TKA | Mean 64.2 (range, 12–237) months for PJI group; mean 35.4 (range, 24–120) months for control group | Successful DAIR vs. primary TKA: no significant differences in mean SF12, KSS (150.1 vs. 160.8), WOMAC (72.1 vs. 75.6) or ROM (110.9 vs. 109); 2-stage revision vs. primary TKA: significantly lower scores for 2SR cohort; Failed DAIR vs. 2SR: No significant differences |
| Aboltins et al., 2015, Australia | Retrospective cohort | 2006–2009 | Included acute post-operative (<3 months after implantation) and acute haematogenous | 41 patients (mix of hip and knee arthroplasty) | Mean 688 days | No statistically significant difference in change between pre-operative and 12-month score of SF12 physical component summary and mental component summary in DAIR and primary arthroplasty |
TKA, total knee arthroplasty; PJI, periprosthetic joint infection; DAIR, debridement, antibiotics and implant retention; 2SR, 2-stage revision; SF12, medical outcomes study short form; WOMAC, Western Ontario and McMaster Universities Arthritis Index; KOOS, Knee Injury and Osteoarthritis Outcome Score; KSCS, knee society clinical score; KSFS, knee society functional score; ROM, range of motion; KKS, Korean Knee Score.