Fig 1.

Sequences of HpARI family members. (A) Alignment of HpARI1, HpARI2, and HpARI3. Gray highlight indicates agreement with consensus. Signal peptide and CCP domains are indicated by red boxes, and coverage of peptides identified by mass spectrometry of HES is indicated by blue boxes. Residues in HpARI2-IL-33 interface are highlighted in red. (B) Transcripts per million (TPM) of HpARI1, HpARI2, and HpARI3 in male and female parasites over a timecourse of infection. Parasites were collected from four to nine mice per data point. Data retrieved from the Sequence Read Archive, PRJNA750155.