Table 6.
Comparison of clinically related measures for rs3756450 G(+) carriers and G(−) carriers in the non-TRS groups.
| Variables | rs3756450 G(+) | rs3756450 G(−) | Statistic values |
|---|---|---|---|
| n = 387 | n = 113 | ||
| Sex: male/female [n] | 180/206 | 63/50 | χ2 = 2.910, p = 0.088 |
| Age at time of blood sampling [years] | 45.26 (15.35) | 44.09 (14.26) | t = 0.715, p = 0.475 |
| Age at onset [years] | 27.19 (10.35) | 27.25 (9.09) | t = 0.046, p = 0.963 |
| Duration of disease [years] | 11.62 (9.79) | 14.31 (11.31) | t = 1.902, p = 0.058 |
| CGI-S | 3.15 (1.07) | 2.79 (0.97) | t = 2.610, p = 0.010 |
| Number of hospitalizations [times] | 1.45 (1.84) | 1.31 (2.27) | t = 0.544, p = 0.587 |
| Work experience following disease onset: Yes/No | 120/104 | 52 / 21 | χ2 = 7.046, p = 0.008 |
| Employment at time of blood sampling: Yes/No | 69/157 | 36 / 36 | χ2 = 9.070, p = 0.003 |
| ECT from onset of illness to time of blood sampling: Yes/No | 6/231 | 3 / 74 | χ2 = 0.389, p = 0.533 |
| Clozapine medication from onset to present: Yes/No | 0/235 | 0 / 76 | - |
| Antipsychotic dose (CP-eq.) [mg] | 477.9 (336.7) | 331.2 (186.6) | t = 3.665, p < 0.001 |
| Monotherapy with antipsychotic: Yes/No | 185 / 51 | 68 / 10 | χ2 = 2.894, p = 0.089 |
Cells with a value and parenthesis indicate mean (SD). Sex was unknown for one patient in the rs3756450 G(+) group.