FIG. 1.

ETO interacts with N-CoR. (A) Schematic diagram of the GAL4–N-CoR, GAL4-ETO, and GAL4-ETO deletion mutant fusion proteins used in the yeast two-hybrid interaction system. Although a fragment of the human N-CoR cDNA was used in these assays, the numbering is in relation to the murine sequence. (B) Growth on complete media of yeast strain PJ69-4A expressing the indicated ETO proteins together with the GAL4 activation domain (AD)–N-CoR fusion protein. (C) Growth of the yeast shown in panel B on adenine (Ade)-deficient media. W.T.; wild type; DBD, DNA binding domain.