FIG. 2.

N-CoR interacts with the ZFs of the MYND domain. (A) Schematic diagram of the GAL4-ETO fusion protein. The amino acid sequence of the MYND domain of ETO is shown. Conserved cysteine and histidine residues that form the predicted ZF motifs are indicated by vertical lines. (B) Growth on complete media of PJ69-4A yeast expressing the indicated ETO proteins together with the GAL4 activation domain–N-CoR fusion protein. (C) Growth of the yeast shown in panel B on adenine (Ade)-deficient media. W.T., wild type; DBD, DNA binding domain.