TABLE 3.
Differences in GTV dose with the standard 3D calculation vs the recalculation of the full 4D‐CT. The 4D calculation algorithm for both the VMAT and DCA techniques directly accounts for the effects of patient respiration on GTV coverage during the ITV‐based treatments.
| 3D | 4D | Average percent difference | p‐value | |
|---|---|---|---|---|
| DCA GTV D95% (cGy) | 6586.4 | 6632.6 | 0.6% | 0.063 |
| VMAT GTV D95% (cGy) | 6467.0 | 6429.9 | −0.5% | 0.31 |
| DCA GTV D1% (cGy) | 7150.4 | 7112.9 | −0.5% | 0.012* |
| VMAT GTV D1% (cGy) | 7124.9 | 7079.4 | −0.6% | 0.085 |
Abbreviations: DCA, dynamic conformal arc; GTV, gross tumor volume; ITV, internal target volume; VMAT, volumetric modulated arc therapy.