Figure 3.

Prediction performance for SARS-CoV-2 infection. Results for SARS-CoV-2 ((b), (e)) are plotted in red while two controls ((a), (c), (d), (f)) for validation of the analysis methodology were plotted in black. Top panels ((a)–(c)) and bottom panels ((d)–(f)) show prediction results obtained by the pattern-based approach and the molecule-based approach, respectively. A control based on birth month ((a), (d)) examines whether subjects were born on the even or the odd months. A control based on breath vs. ambient air ((c), (f)) examines whether spectroscopy data were measured for inhaled air or exhaled breath. Obtained AUCs are reported on the figures. Respective assignment of the response classes for the two controls to positive and negative was done at random and does not carry any particular meaning. Details on cross-validations are described in the main text. TP, true positive; FP, false positive.