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. 2024 Mar 11;46(1):2327495. doi: 10.1080/0886022X.2024.2327495

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© 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 1. — Quercetin’s effects on DKD rats’ renal function and tissue injury. (A) Diabetic kidney disease (DKD) rat model establishment with STZ and treatment regimen. (B) Post-12-week blood glucose level following quercetin or Fer-1 administration. Measurements at 12 weeks included urine albumin (C), creatinine (D), and UCAR (E). Kidney weight (F), body weight (G), and kidney/body weight ratio (H) were also assessed. (I) Kidney sections stained with HE (upper), and PAS (bottom) across groups (scale bar = 50 μm). Groups: CON (control), DKD (model), DKD + QCT (quercetin-treated), DKD + Fer-1 (Ferrostatin-1-treated). Mean data ± SD are shown. Significance levels: ****p < 0.0001; ***p < 0.001; **p < 0.01; *p < 0.05 via one-way ANOVA.