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. 2021 Sep 28;46(9):932–941. doi: 10.11817/j.issn.1672-7347.2021.210413

Figure 5. Schematic illustration.

Figure 5

CYPs/EETs are highly expressed in PDAC and EETs inhibit the erastin-induced ferroptosis in a PPARγ-dependent manner in PANC-1 cells. ARA: Arachidonic acid; CYP2J2: Cytochrome P4502J2; EETs: Epoxyeicosatrienoic acids; PPARγ: Peroxisome proliferation-activated receptor γ; GPX4: Glutathione peroxidase; PDAC: Pancreatic ductal adenocarcinoma.