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. 2024 Mar 5;16(5):1056. doi: 10.3390/cancers16051056
c-MET Mesenchymal–epithelial transition factor
HGF Hepatocyte growth factor
kDa Kilodalton
MET MAPK/ERK
PTK Protein tyrosine kinase
GEFs Guanine exchange factors
GTP Guanosine triphosphate
PIP2 Phosphatidylinositol-4,5-diphosphate
PIP3 Phosphatidylinositol-3,4,5-triphosphate
Akt protein kinase B
SHP2 SH2 domain-containing tyrosine phosphatase
SHC SH2 domain-containing transforming protein
GRB2 Growth factor receptor-bound protein 2
SOS Son of sevenless
MEK Mitogen-activated protein kinase kinase
ERK Extracellular signal-regulated kinases
PI3K Phosphoinositide 3-kinase
Akt Protein kinase B
BAD BCL-2 antagonist of cell death
MDM2 Murine double minute 2
STAT3 Signal transducer and activator of transcription 3
HIF-1 Hypoxia-inducible factor-1
HIF-1α Hypoxia-inducible factor 1-alpha
mTOR Mammalian target of rapamycin