Table 2.
Histopathological features of patients with DTC, according to their BMI group.
| Normal Weight | Overweight | Obesity | p Value * | |||
|---|---|---|---|---|---|---|
| BMI 18.5–24.9 | BMI 25–29.9 | BMI ≥ 30 | ||||
| N = 66, 31.3% | N = 81, 38.4% | N = 64, 30.3% | ||||
| T | pT (n, %) | pT 1–2 | 55, 83.33% | 63, 77.78% | 50, 78.13% | * 0.763 |
| a 0.484 | ||||||
| pT 3–4 | 11, 16.67% | 17, 20.99% | 13, 20.31% | b 0.563 | ||
| c 0.929 | ||||||
| Histological sub-type (n, %) | PTC | 60, 90.91% | 75, 92.59% | 60, 93.75% | * 1 | |
| a 1 | ||||||
| FTC | 5, 7.58% | 6, 7.41% | 4, 6.25% | b 1 | ||
| c 1 | ||||||
| PTC variant (n, %) | Classic | 32, 48.48% | 25, 30.86% | 20, 31.25% | * 0.62 | |
| a 0.6 | ||||||
| Follicular | 24, 36.36% | 41, 50.62% | 30, 46.88% | b 0.332 | ||
| Aggressive ¥ | 4, 6.06% | 9, 11.11% | 10, 15.63% | c 0.69 | ||
| Multifocality (n, %) | 26, 39.39% | 38, 46.91% | 24, 37.5% | * 0.486 | ||
| a 0.403 | ||||||
| b 0.771 | ||||||
| c 0.255 | ||||||
| Any extrathyroidal extension (n, %) | 14, 21.21% | 23, 28.4% | 20, 31.25% | * 0.399 | ||
| a 0.345 | ||||||
| b 0.232 | ||||||
| c 0.717 | ||||||
| LN | LN MTS (n, %) | No | 52, 78.79% | 59, 72.84% | 41, 64.06% | * 0.349 |
| a 0.372 | ||||||
| N1a | 6, 9.09% | 14, 17.28% | 13, 20.31% | b 0.129 | ||
| N1b | 7, 10.61% | 8, 9.88% | 9, 14.06% | c 0.576 | ||
| Bilateral lateral neck LN MRS (n, %) | 0, 0% | 2, 2.47% | 3, 4.69% | * 0.233 | ||
| a 0.502 | ||||||
| b 0.116 | ||||||
| c 0.655 | ||||||
| LN diameter ≥ 3 cm # (n, %) | 2, 3.03% | 0, 0% | 4, 6.25% | * 0.037 | ||
| a 0.2 | ||||||
| b 0.437 | ||||||
| c 0.036 | ||||||
| Extra-nodal extension # (n, %) | 4, 6.06% | 7, 8.64% | 8, 12.5% | * 0.436 | ||
| a 0.754 | ||||||
| b 0.204 | ||||||
| c 0.46 | ||||||
| Distal MTS (n, %) | 4, 6.06% | 2, 2.47% | 0, 0% | * 0.134 | ||
| a 0.407 | ||||||
| b 0.119 | ||||||
| c 0.504 | ||||||
* Comparison of all 3 sub-groups, a—overweight versus normal weight, b—obese versus normal weight, c—obese versus overweight; ¥ tall cell, columnar, and insular variants of PTC together with moderately and poorly differentiated variants; # one or more. Abbreviations: DTC—differentiated thyroid carcinoma, BMI—body mass index (body weight [Kg] divided by the squire of height [meters]), T—primary tumor characteristics, PTC—papillary thyroid carcinoma, FTC—follicular thyroid carcinoma, LN—lymph node/s, MTS—metastasis.