Table 3.
Treatment modalities and follow-up data of patients with DTC, according to their BMI group.
Normal Weight | Overweight | Obesity | p Value * | ||
---|---|---|---|---|---|
BMI 18.5–24.9 | BMI 25–29.9 | BMI ≥ 30 | |||
N = 66, 31.3% | N = 81, 38.4% | N = 64, 30.3% | |||
Thyroid surgery (n,%) | Partial | 23, 34.85% | 15, 18.52% | 17, 26.56% | * 0.08 |
a 0.024 | |||||
Complete | 43, 65.15% | 66, 81.48% | 47, 73.44% | b 0.306 | |
c 0.246 | |||||
RAI treatment (n,%) | No | 31, 46.97% | 30, 37.04% | 29, 45.31% | * 0.839 |
a 0.532 | |||||
30 mCi | 10, 15.15% | 16, 19.75% | 11, 17.19% | b 0.948 | |
≥100 mCi | 21, 31.82% | 27, 33.33% | 20, 31.25% | c 0.697 | |
Risk of disease recurrence ¥ (n,%) | Low | 37, 56.06% | 36, 44.44% | 29, 45.31% | * 0.363 |
a 0.228 | |||||
Intermediate or high | 25, 37.88% | 39, 48.15% | 30, 46.88% | b 0.276 | |
c 1 | |||||
Response to treatment § (n,%) | Excellent | 49, 74.24% | 57, 70.37% | 37, 57.81% | * 0.108 |
a 0.79 | |||||
Incomplete # | 7, 10.61% | 7, 8.64% | 12, 18.75% | b 0.111 | |
c 0.056 | |||||
Additional intervention @ (n,%) | 0, 0% | 5, 6.17% | 5, 7.81% | * 0.049 | |
a 0.062 | |||||
b 0.024 | |||||
c 0.75 |
* Comparison of all 3 sub-groups, a—overweight versus normal weight, b—obese versus normal weight, c—obese versus overweight; ¥ risk of structural disease recurrence; § response to treatment as was documented at the last follow-up visit; # biochemical and/or structural [28]; @ second thyroid operation, and/or neck dissection, and/or second RAI treatment, and/or external beam irradiation. Due to missing data in some variables the total percent per column might not summarize to 100%. Abbreviations: DTC—differentiated thyroid carcinoma, BMI—body mass index (body weight [Kg] divided by the square of height [meters]), RAI—radioactive iodine, mCi—millicurie.