Table 5.
Association between triglycerides/HDL-C as continuous variables and selected histopathological features of patients with DTC aged 30–70 years at the time of the index operation.
| Histopathological Feature | Sub-Categories | Unadjusted | Adjusted @ |
|---|---|---|---|
| Odds Ratio (95% CI) * | Odds Ratio (95% CI) * | ||
| Histological sub-type and variants | PTC classic variant | 1.00 (REF) | 1.00 (REF) |
| PTC—follicular variant | 1.13 (0.942–1.355) | 1.125 (0.922–1.372) | |
| Aggressive variant ¥ of PTC and/or FTC | 1.302 (1.047–1.619) | 1.269 (1.001–1.61) | |
| Extrathyroidal extension | None | 1.00 (REF) | 1.00 (REF) |
| Microscopic | 1.007 (0.839–1.208) | 0.999 (0.819–1.219) | |
| Gross | 0.839 (0.581–1.211) | 0.716 (0.465–1.104) | |
| Vascular invasion | No | 1.00 (REF) | 1.00 (REF) |
| Yes | 0.995 (0.805–1.229) | 0.999 (0.796–1.255) | |
| Multifocality | No | 1.00 (REF) | 1.00 (REF) |
| Yes | 1.137 (0.975–1.326) | 1.072 (0.908–1.266) | |
| Lateral neck LN MTS | No | 1.00 (REF) | 1.00 (REF) |
| Yes | 1.029 (0.658–1.61) | 0.931 (0.572–1.517) | |
| LN MTS ≥ 3 cm | No | 1.00 (REF) | 1.00 (REF) |
| Yes | 1.25 (0.893–1.749) | 1.163 (0.796–1.699) | |
| Extra-nodal extension | No | 1.00 (REF) | 1.00 (REF) |
| Yes | 1.101 (0.845–1.435) | 1.022 (0.759–1.376) | |
| Distal MTS | No | 1.00 (REF) | 1.00 (REF) |
| Yes | 1.146 (0.652–2.016) | 1.134 (0.481–2.675) |
@ Adjusted for age, sex, and ethnicity; * bolded for p ≤ 0.05; ¥ tall cell, columnar, and insular variants of PTC together with moderately and poorly differentiated variants. Abbreviations: HDL-C—high-density lipoprotein–cholesterol, CI—confidence interval, PTC—papillary thyroid carcinoma, FTC—follicular thyroid carcinoma, LN—lymph node/s, MTS—metastasis.