Table 1.
Standardized quality assessment of reviewed studies.
| Clinical Trials | |||||||
|---|---|---|---|---|---|---|---|
| Study | Randomized and Blinded? |
Allocation Concealment |
Baseline Group Similarities |
Dropout Rate |
Intervention Control |
Adherence Assurance |
Sample Size and Power Reported |
| Mondul et al. [12] | Yes | Yes | Yes | NR | Yes | Yes | Yes |
| Omenn et al. [13] | Yes | Yes | Yes | NR | Yes | Yes | Yes |
| Klein et al. [14] | Yes | Yes | Yes | NR | Yes | Yes | Yes |
| Cohorts/Cross-Sectional Studies | |||||||
| Study |
Clear Objective
and Study Population |
Sample Size
and Power Reported |
Sufficient
Follow-Up Period |
Leveling
of Exposure |
Exposure
Measured before Outcome |
Multiple
Exposure Assessments |
Confounding
Variables Considered |
| Brasky et al. [15] | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| Hirsch et al. [16] | Yes | NR | NA | CD | NA | No | Yes |
| Chen et al. [17] | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| Kefield et al. [18] | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| Zhang et al. [19] | Yes | Yes | Yes | Yes | Yes | Yes | NR |
CD: Cannot Determine, NA: Not Applicable, NR: Not Reported.