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EAE treatment ameliorated histological damage and Aβ accumulation in the hippocampal area of 5xFAD mice. (A) Representative images of brain slices stained by hematoxylin and eosin. Upper panel, hippocampal area of the mouse brain. Lower left panel (boxed in green), CA1 region. Lower right panel (boxed in yellow), DG region. (B,C) Hippocampal region stained by thioflavin S. Representative images at 100× magnification (B) and quantification data for thioflavin S-staining intensity (C).
