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Macroscopic monitoring of mice during intraperitoneal injections of D-VC and L-VC for 18 day. The study included 15 adult female CD1 mice. The mice received intraperitoneal injections of D-VC and L-VC at a dose of 9.2 g/kg daily once a day for 18 days. Control animals received injections of PBS. The formation of trophic ulcers on the back and pelvis of the mice of L-VC injected group: damaged epithelium and basal layers of the skin, inflammatory processes, scabs and tissue necrosis.
