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Abnormal nuclear ((a), 30×) or cytoplasmic ((b), 30×) staining with original PD-L1 LDT IHC in cases n° 2 and 3, respectively. Case n° 9 was affected by major technical issues, as per board judgment, showing a less intense but sharper membrane staining with the LDT assay ((c), 30×), as compared to the CDx-based preparation ((d), 30×).
