FIG. 5.

Structure (A) and sequence (B) of a 5′-flanking region of the rat CaSR by comparison to the untranslated region (UTR) of the rat CaSR. The sequence of 1,095 bp of the 5′-flanking region of the rat CaSR was obtained by nested PCR. The sequence of the untranslated region of the rat CaSR cDNA is from Riccardi et al. (52). The boxed region in panel B denotes a region of sequence identity between the two sequences. Thick underlining between bp −201 and −192 denotes the putative TTF-1 CaSR-C site. Thin underlining at bp −544 to −535 and bp −249 to −240 denotes the putative TTF-1 CaSR-A and CaSR-B sites, respectively.