Table 1.
Study | Study Design | Atropine %, Treatment Time |
n | Age (years) | Baseline SE (D) | Baseline AL (mm) | Country |
---|---|---|---|---|---|---|---|
J.C. Yam 2023 [18] | RCT | 0.05%, 2 y | 160 | 6.86 ± 1.42 | 0.50 ± 0.33 | 22.82 ± 0.72 | Hong Kong |
0.01%, 2 y | 159 | 6.88 ± 1.35 | 0.51 ± 0.33 | 22.89 ± 0.70 | |||
Placebo, 2 y | 155 | 6.75 ± 1.27 | 0.53 ± 0.31 | 22.80 ± 0.64 | |||
W. Wang 2023 [17] | RCT | 0.01%, 6 m | 30 | 8.60 ± 1.72 | −0.19 ± 0.28 | 23.59 ± 0.77 | China |
Placebo, 6 m | 30 | 8.50 ± 1.74 | −0.21 ± 0.32 | 23.61 ± 0.75 | |||
J. Jethani 2022 [26] | RCT | 0.01%, 2 y | 30 | 7.70 ± 2.10 | N/A | 20.80 ± 0.60 | India |
Placebo, 2 y | 30 | 7.20 ± 1.90 | 21.00 ± 0.50 | ||||
P.C. Fang 2010 [16] | Non-RCT | 0.025%, 18.4 m * | 24 | 7.60 ± 1.70 | −0.31 ± 0.45 | N/A | Taiwan |
Placebo, 16.3 m * | 26 | 8.20 ± 2.10 | −0.17 ± 0.50 |
Note: m: months; y: years; N/A: not available. All data are reported as the mean ± SD, if not marked otherwise. * Average follow-up time.